%0 Journal Article %@ 1929-073X %I JMIR Publications %V 13 %N %P e48396 %T The Association Between Depressive Symptoms and the Weekly Duration of Physical Activity Subset by Intensity and Domain: Population-Based, Cross-Sectional Analysis of the National Health and Nutrition Examination Survey From 2007 to 2018 %A Boparai,Josheil K %A Dunnett,Sarah %A Wu,Michelle %A Tassone,Vanessa K %A Duffy,Sophie F %A Zuluaga Cuartas,Valentina %A Chen,Ziming %A Jung,Hyejung %A Sabiston,Catherine M %A Lou,Wendy %A Bhat,Venkat %+ Interventional Psychiatry Program, St. Michael's Hospital, 193 Yonge Street, Floor Number 6-013, Toronto, ON, M5B1M8, Canada, 1 4163604000 ext 76404, venkat.bhat@utoronto.ca %K depressive disorder %K exercise %K physical activity intensity %K recreational physical activity %K work-related physical activity %K National Health and Nutrition Examination Survey %K NHANES %K nutrition surveys %K recreational activity %K physical activity %K depression %D 2024 %7 5.7.2024 %9 Original Paper %J Interact J Med Res %G English %X Background: Prior literature suggests a dose-response relationship between physical activity (PA) and depressive symptoms. The intensity and domain of PA are suggested to be critical to its protective effect against depression; however, existing literature has shown mixed results. Objective: The purpose of this population-based study is to examine the associations between depressive symptoms and weekly duration of (1) total PA and (2) PA subset by intensity, domain, or both. Methods: A cross-sectional analysis of National Health and Nutrition Examination Survey data from 2007 to 2018 was conducted using multivariable logistic and linear regression models and survey weights. Participants (N=29,730) were 20 years and older and completed the Physical Activity Questionnaire and Depression Screener. The primary outcome was the presence of depressive symptoms, and the secondary outcomes were cognitive-affective and somatic symptoms of depression. Results: Participants (N=29,730) had a weighted mean age of 47.62 (SD 16.99) years, and 15,133 (51.34%) were female. On average, participants without depressive symptoms engaged in 10.87 hours of total PA per week, whereas participants with depressive symptoms engaged in 8.82 hours (P<.001). No significant associations were seen between the weekly duration of total PA and depressive symptom odds, somatic, or cognitive-affective symptoms (all P>.05). Participants with an increased weekly duration of recreational PA had decreases in depressive symptom odds (adjusted odds ratio [aOR] 0.965, 95% CI 0.944-0.986) and in somatic (adjusted coefficient [aβ]=–0.016, 95% CI –0.022 to –0.009) and cognitive-affective (aβ=–0.015, 95% CI –0.023 to –0.007) symptoms. When recreational PA was subset by intensity, participants with an increased weekly duration of vigorous-intensity recreational PA had decreases in depressive symptom odds (aOR 0.926, 95% CI 0.883-0.972) and in somatic (aβ=–0.021, 95% CI –0.032 to –0.010) and cognitive-affective (aβ=–0.022, 95% CI –0.035 to –0.009) symptoms. However, significant associations were not seen for the weekly duration of work-related, moderate- or vigorous-intensity PAs (all P>.05). Conclusions: Findings suggest that recreational, not work-related PA is associated with reduced symptoms of depression. Future studies should explore the impact of the different types and contexts of PA on depressive symptomatology. %R 10.2196/48396 %U https://www.i-jmr.org/2024/1/e48396 %U https://doi.org/10.2196/48396