%0 Journal Article %@ 1929-073X %I JMIR Publications %V 13 %N %P e56207 %T Dynamics of Blood Lipids Before, During, and After Diurnal Fasting in Inactive Men: Quasi-Experimental Study %A Aljaloud,Khalid %A Al-Barha,Naif %A Noman,Abeer %A Aldayel,Abdulaziz %A Alsharif,Yahya %A Alshuwaier,Ghareeb %+ Department of Exercise Physiology, College of Sport Sciences and Physical Activity, King Saud University, P O Box 2454, Riyadh, 11451, Saudi Arabia, 966 0118063100, khaljaloud@ksu.edu.sa %K cardiovascular diseases %K cardiovascular risk factors %K lipids %K glucose measurement %K fasting %K Ramadan %K body composition %D 2024 %7 17.10.2024 %9 Original Paper %J Interact J Med Res %G English %X Background: There is a lack of investigation into the dynamics of blood lipids before, during, and after diurnal fasting, especially in inactive men. Objective: This study determined dynamic changes in blood lipids in inactive men before, during, and after they underwent diurnal fasting. Methods: A total of 44 young men aged a mean 27.6 (SD 5.8) years were recruited to evaluate their habitual physical activity and diet using a questionnaire developed for this study. Body composition was evaluated using a bioelectrical impedance analysis machine (Tanita BC-980). An 8-ml blood sample was collected to evaluate blood lipids and glucose. All measurements were taken 2-3 days before Ramadan, during Ramadan (at week 2 and week 3), and 1 month after Ramadan. A 1-way repeated measures ANOVA was used to compare the measured variables before, during, and after the month of Ramadan. When a significant difference was found, post hoc testing was used. Differences were considered significant at P<.05. Results: There was a significant reduction in low-density lipoprotein during Ramadan compared to before and after Ramadan (83.49 mg/dl at week 3 vs 93.11 mg/dl before Ramadan [P=.02] and 101.59 mg/dl after Ramadan [P=.007]). There were significant elevations in fasting blood glucose (74.60 mmol/L before Ramadan vs 81.52 mmol/L at week 3 [P=.03] and 86.51 mmol/L after Ramadan [P=.01]) and blood pressure (109 mm Hg before Ramadan vs 114 mm Hg after Ramadan; P=.02) reported during and even after the month of Ramadan, although both fasting blood glucose and blood pressure were within normal levels. Conclusions: Ramadan fasting could be an independent factor in reducing low-density lipoprotein. Further investigations are encouraged to clarify the impact of diurnal fasting on blood lipids in people with special conditions. %R 10.2196/56207 %U https://www.i-jmr.org/2024/1/e56207 %U https://doi.org/10.2196/56207