%0 Journal Article %@ 1929-073X %I JMIR Publications %V 14 %N %P e65844 %T Exploring 97 Years of Aedes aegypti as the Vector for Dengue, Yellow Fever, Zika, and Chikungunya (Diptera: Culicidae): Scientometric Analysis %A Cheong,Yoon Ling %A Mohd Ghazali,Sumarni %A Mat Hashim,Mohd Hazilas %A Che Ibrahim,Mohd Khairuddin %A Amran,Afzufira %A Tiunh,Tsye Yih %A Lim,Hui Li %A Cheah,Yong Kang %A Gill,Balvinder Singh %A Lim,Kuang Hock %+ Biomedical Museum Unit, Special Resource Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Jalan Pahang, Kuala Lumpur, 50588, Malaysia, 60 326162666 ext 2810, cheongyl@moh.gov.my %K relative growth rate %K vector control %K collaboration index %K bibliometric %K Aedes aegypti %K Scopus %K co-occurrence %K author %K dengue %K Zika %D 2025 %7 23.4.2025 %9 Original Paper %J Interact J Med Res %G English %X Background: Aedes aegypti is an important vector that transmits dengue, Zika, chikungunya, and yellow fever viruses. Although research on Aedes aegypti has been conducted for decades, scientometric studies on Aedes aegypti are scarce, are limited to regions, and cover short periods. Thus, there is still a knowledge gap in the current trend, research focuses and directions, leading authors and collaboration, journal and citation impacts, countries, and worldwide collaborations. Objective: The objectives of the study are to investigate the research trend, focus and directions, citation impact, leading authors and collaboration, journals, and countries of the published works on Aedes aegypti to inform the current knowledge gaps and future direction of the control of the vector. Methods: In this study, we searched the Scopus database for articles on Aedes aegypti published from the year 1927 until April 5th, 2024, and included articles, reviews, books, and book chapters that were written in English. A total of 16,247 articles in 160 journals with 481,479 citations were included. Inconsistencies in authors’ names were checked and cleaned using OpenRefine. The data were grouped into 4 periods; years 1927-1999, 2000-2009, 2010-2019, and 2020-2023. The relative growth rate and doubling time of publications were calculated. The analysis was conducted using VOSviewer, R bibliometrics, and citeSpace. Results: The overall RGR was 0.1. Doubling time increased from 9.3 in 1978-1998 to 12.1 in 2000-2009. The main research clusters were “using Wolbachia,” “Dengue Zika,” “worldwide diversity,” “community support,” “larvicidal activity,” “mosquito genotype-dependent,” and “sterile insect technique.” Journal of Medical Entomology was the leading journal (758/16,247, 4.7%). The most cited articles were authored by Halstead SB and team in Science (N=1355) and Kraemer MU and team in eLife (N=1324). The United States (5806/23,538, 24.7%) and Brazil (2035/23,538, 8.6%) were the top countries. Gubler DJ was the top co-cited author (n=2892) from 2000 to 2019. The co-cited author cluster patterns informed the significant specialty research on Aedes aegypti across time. Authors from various specialized research fields tended to collaborate across countries, especially neighboring countries. Countries with more research funding on the study of Aedes aegypti published more papers. Conclusions: Researchers or entomologists could understand the current knowledge gap on Aedes aegypti and plan for future research pathways. This study contributed to the public health stakeholders in improving the vector control interventions and elucidated the extent of research subject areas. %R 10.2196/65844 %U https://www.i-jmr.org/2025/1/e65844 %U https://doi.org/10.2196/65844