TY - JOUR AU - Inderstrodt, Jill AU - Stumpff, Julia C AU - Smollen, Rebecca C AU - Sridhar, Shreya AU - El-Azab, Sarah A AU - Ojo, Opeyemi AU - Bowns, Brendan AU - Haggstrom, David A PY - 2025 DA - 2025/3/25 TI - Informatics Interventions for Maternal Morbidity: Scoping Review JO - Interact J Med Res SP - e64826 VL - 14 KW - scoping review KW - maternal morbidity KW - medical informatics KW - clinical informatics KW - mother KW - pregnant KW - perinatal KW - GDM KW - preeclampsia KW - maternity KW - gestational diabetes mellitus AB - Background: Women have been entering pregnancy less healthy than previous generations, placing them at increased risk for pregnancy complications. One approach to ensuring effective monitoring and treatment of at-risk women is designing technology-based interventions that prevent maternal morbidities and treat perinatal conditions. Objective: This scoping review evaluates what informatics interventions have been designed and tested to prevent and treat maternal morbidity. Methods: MEDLINE, Embase, and Cochrane Library were searched to identify relevant studies. The inclusion criteria were studies that tested a medical or clinical informatics intervention; enrolled adult women; and addressed preeclampsia, gestational diabetes mellitus (GDM), preterm birth, Centers for Disease Control and Prevention–defined severe maternal morbidity, or perinatal mental health conditions. Demographic, population, and intervention data were extracted to characterize the technologies, conditions, and populations addressed. Results: A total of 80 studies were identified that met the inclusion criteria. Many of the studies tested for multiple conditions. Of these, 73% (60/82) of the technologies were tested for either GDM or perinatal mental health conditions, and 15% (12/82) were tested for preeclampsia. For technologies, 32% (28/87) of the technologies tested were smartphone or tablet applications, 26% (23/87) were telehealth interventions, and 14% (12/87) were remote monitoring technologies. Of the many outcomes measured by the studies, almost half (69/140, 49%) were patient physical or mental health outcomes. Conclusions: Per this scoping review, most informatics interventions address three conditions: GDM, preeclampsia, and mental health. There may be opportunities to treat other potentially lethal conditions like postpartum hemorrhage using proven technologies such as mobile apps. Ample gaps in the literature exist concerning the use of informatics technologies aimed at maternal morbidity. There may be opportunities to use informatics for lesser-targeted conditions and populations. SN - 1929-073X UR - https://www.i-jmr.org/2025/1/e64826 UR - https://doi.org/10.2196/64826 DO - 10.2196/64826 ID - info:doi/10.2196/64826 ER -