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Real-World Effectiveness of Glucose-Guided Eating Using the Data-Driven Fasting App Among Adults Interested in Weight and Glucose Management: Observational Study

Real-World Effectiveness of Glucose-Guided Eating Using the Data-Driven Fasting App Among Adults Interested in Weight and Glucose Management: Observational Study

During the first 3 days of app use, participants are instructed to eat normally but to test their glucose levels before every eating occasion. Reported preprandial glucose levels during this time are averaged to establish a baseline glucose threshold. After this initial phase, users are encouraged to observe their hunger sensations and test their preprandial glucose levels only when hungry, and to delay eating until their glucose levels fall below their personalized threshold (ie, glucose-guided eating).

Michelle R Jospe, Martin Kendall, Susan M Schembre, Melyssa Roy

JMIR Form Res 2025;9:e65368

High-Intensity Interval Training for Individuals With Isolated Impaired Fasting Glucose: Protocol for a Proof-of-Concept Randomized Controlled Trial

High-Intensity Interval Training for Individuals With Isolated Impaired Fasting Glucose: Protocol for a Proof-of-Concept Randomized Controlled Trial

CGM: continuous glucose monitoring; HIIT: high-intensity interval training; i-IFG: isolated impaired fasting glucose; OGTT: oral glucose tolerance test; REDCap: Research Electronic Data Capture. Potential participants will be identified using Emory’s electronic health care records system, known as “My Chart.”

Sathish Thirunavukkarasu, Thomas R Ziegler, Mary Beth Weber, Lisa Staimez, Felipe Lobelo, Mindy L Millard-Stafford, Michael D Schmidt, Aravind Venkatachalam, Ram Bajpai, Farah El Fil, Maria Prokou, Siya Kumar, Robyn J Tapp, Jonathan E Shaw, Francisco J Pasquel, Joe R Nocera

JMIR Res Protoc 2025;14:e59842

Now I can see it works!” Perspectives on Using a Nutrition-Focused Approach When Initiating Continuous Glucose Monitoring in People with Type 2 Diabetes: Qualitative Interview Study

Now I can see it works!” Perspectives on Using a Nutrition-Focused Approach When Initiating Continuous Glucose Monitoring in People with Type 2 Diabetes: Qualitative Interview Study

Moreover, continuous glucose monitoring (CGM) has also been shown to improve glycemic outcomes for people with T2 D [3]. CGM can provide a comprehensive assessment of the impact of foods and other behaviors on glucose in real time and over the course of time. People with T2 D may benefit from using CGM data to guide food choices that help achieve their desired glycemic goals, including time in range (TIR; percent time with glucose levels between 70-180 mg/d L).

Holly J Willis, Maren S G Henderson, Laura J Zibley, Meghan M JaKa

JMIR Diabetes 2025;10:e67636

The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial

The Effect of Effort During a Resistance Exercise Session on Glycemic Control in Individuals Living With Prediabetes or Type 2 Diabetes: Protocol for a Crossover Randomized Controlled Trial

Type 2 diabetes (T2 D) is a disease in which peripheral insulin resistance associated with pancreatic beta-cell dysfunction leads to chronically elevated blood glucose levels [1]. If left unchecked over long periods of time, high glucose levels lead to vascular complications such as increased risk of cardiovascular diseases, diabetic nephropathy, neuropathy, retinopathy, and lower limb amputation [2].

Marissa Ramirez, Maja Gebauer, Christine Mermier, Jonathan Peter Little, Luotao Lin, Gabriel Palley, Yu Yu Hsiao, Roberto Ivan Mota Alvidrez, Zach A Mang, Fabiano Trigueiro Amorim, Valmor Tricoli, Flavio De Castro Magalhaes

JMIR Res Protoc 2024;13:e63598

A Culturally Sensitive Mobile App (DiaFriend) to Improve Self-Care in Patients With Type 2 Diabetes: Development Study

A Culturally Sensitive Mobile App (DiaFriend) to Improve Self-Care in Patients With Type 2 Diabetes: Development Study

In total, 2 studies have addressed the importance of culturally sensitive apps for diabetes management to improve blood glucose in Asian people with diabetes [14,15]. They identified the gap in culturally tailored content and features that address specific dietary habits, lifestyle practices, and health beliefs of diverse ethnic populations.

Peeranuch LeSeure, Elizabeth Chin, Shelley Zhang

JMIR Diabetes 2024;9:e63393

Consequences of Data Loss on Clinical Decision-Making in Continuous Glucose Monitoring: Retrospective Cohort Study

Consequences of Data Loss on Clinical Decision-Making in Continuous Glucose Monitoring: Retrospective Cohort Study

Improved glucose sensing techniques have led to the increased availability of continuous glucose monitoring (CGM) technology for patients with diabetes. These minimally invasive sensors measure the glucose concentration of the interstitial fluid every 1 or 5 minutes, representing the blood glucose concentration with an average delay of 10-12 minutes [1,2]. CGM provides insights into glucose concentration fluctuations throughout the day and enables comparisons over time using predefined glucose metrics.

Niala den Braber, Carlijn I R Braem, Miriam M R Vollenbroek-Hutten, Hermie J Hermens, Thomas Urgert, Utku S Yavuz, Peter H Veltink, Gozewijn D Laverman

Interact J Med Res 2024;13:e50849

Cardiovascular Comorbidities in COVID-19: Comprehensive Analysis of Key Topics

Cardiovascular Comorbidities in COVID-19: Comprehensive Analysis of Key Topics

“Disorders of Glucose Metabolism” follow (with an increase of ∆f[Me SH]=1.14% and a ratio of R[Me SH]=2.46), and “Disorders of Acid-Base Balance” come in third (with an increase of ∆f[Me SH]=0.06% and a ratio of R[Me SH]=1.47). Comparative analysis of level 1 (LV1) subbranch disease descriptor frequencies in COVID-19–related articles.

Rene Markovič, Luka Ternar, Tim Trstenjak, Marko Marhl, Vladimir Grubelnik

Interact J Med Res 2024;13:e55699

Exploring the Impact of Device Sourcing on Real-World Adherence and Cost Implications of Continuous Glucose Monitoring in Patients With Diabetes: Retrospective Claims Analysis

Exploring the Impact of Device Sourcing on Real-World Adherence and Cost Implications of Continuous Glucose Monitoring in Patients With Diabetes: Retrospective Claims Analysis

Managing diabetes involves consistent and ongoing care due to its chronic nature, and blood glucose monitoring has long been the gold standard for patients with diabetes to self-monitor their blood glucose levels for decades [5]. A successor to the familiar periodic fingerstick monitoring technique, continuous glucose monitoring enables individuals with diabetes to self-monitor their blood glucose continuously day and night, eliminating the burden of frequent, unpleasant finger pricks [5].

Jason C Allaire, Consuela Dennis, Arti Masturzo, Steven Wittlin

JMIR Diabetes 2024;9:e58832

Biochemical Changes in Adult Male Gamers During Prolonged Gaming: Pilot Study

Biochemical Changes in Adult Male Gamers During Prolonged Gaming: Pilot Study

The parameters that have been investigated most thoroughly are blood glucose and cortisol. For blood glucose levels, gaming does not appear to increase glucose levels within the first 20 minutes of a gaming session [15,16]. Chaput et al [15] reported that gaming increased blood glucose levels after 40 minutes of a 60-minute gaming session. Cortisol has been used as a marker of both physiological and mental stress during gaming [17-19].

Kasper Bygum Krarup, Johannes Riis, Morten Mørk, Hien Thi Thu Nguyen, Inge Søkilde Pedersen, Søren Risom Kristensen, Aase Handberg, Henrik Bygum Krarup

Interact J Med Res 2024;13:e46570

Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study

Participatory Development of an Integrated, eHealth-Supported, Educational Care Pathway (Diabetes Box) for People With Type 2 Diabetes: Development and Usability Study

Traditionally, DSME is done face-to-face, but digital tools can facilitate health behavior change and significantly improve glucose regulation in patients with T2 D [17]. Effective digital tools are self-monitoring (eg, continuous glucose monitoring [CGM]) and telemonitoring by health care professionals (HCPs) [18,19]. Mobile phone apps providing automated feedback can also be effective in improving lifestyle modification and glucose regulation for people with T2 D [20].

Daan Leonhard de Frel, Mariëlle A Schroijen, Jiska J Aardoom, Wesley van Gils, Sasja D Huisman, Veronica R Janssen, Anke Versluis, Maaike S Kleinsmann, Douwe E Atsma, Hanno Pijl

JMIR Hum Factors 2024;11:e45055