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Skip search results from other journals and go to results- 9 JMIR Research Protocols
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Childhood brain/CNS tumors were more commonly reported in Africa, with 14.2% incidence rates (IRs) of new global brain/CNS tumor cases and 16.9% of deaths reported in 2022 for children aged 0-18 years old [11,12]. An additional source of underreporting of brain and CNS tumors in Africa is the scarcity of well-established tumor registries [9,10].
JMIR Res Protoc 2025;14:e66978
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Precision oncology is a rapidly evolving field in which patient treatment is determined by the DNA signature of the tumor. Advancements in genome-sequencing techniques, molecular analysis, and a growing body of clinical trials, have all allowed for the field to integrate more easily into oncology research [1]. Using these techniques to optimize treatment has been shown to be associated with favored clinical outcomes [1].
J Med Internet Res 2025;27:e64364
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Artificial Intelligence in Lymphoma Histopathology: Systematic Review
Our review encompasses research that focuses on individual diagnostic factors, such as histological subtypes, as well as studies that perform computer-assisted tasks like tumor segmentation. We also assessed the clinical utility of these AI methods with consideration of potential biases. The objective of this review is to provide valuable insights and actionable recommendations based on the existing body of literature.
J Med Internet Res 2025;27:e62851
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Pleural fluid cytology has an overall sensitivity of 58.2% (range 20.5%-86%), with the yield depending on factors like the mechanism of effusion, type of primary tumor, number of specimens, and skill of the cytopathologist [12,13]. The diagnostic yield of closed pleural biopsy in MPE ranges from 39% to 75%, which is inferior to cytology since the blind procedure may sometimes yield insufficient or a nonrepresentative sample [8].
JMIR Res Protoc 2024;13:e56592
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Currently, GC staging is performed according to the Union for International Cancer Control and American Joint Committee on Cancer tumor‐node‐metastasis (TNM) staging system [3]. This system could be used to stratify cancer prognosis. As part of the TNM staging system, T staging based on the tumor depth of GC is crucial for developing treatment plans.
J Med Internet Res 2024;26:e56851
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Possible treatment options for epithelioid hemangioendothelioma based on retrospective studies of tumor involvement and case outcomes [9].
a R0: microscopic negative margins.
b R1: gross negative margins.
The heterogeneity of EHE is also demonstrated in its variable course; EHE can be unpredictable, at times being indolent and at other times very aggressive [7]. Given the uncertain course of the disease, joint decision-making between the patient and physician is necessary.
JMIR Dermatol 2024;7:e52493
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Unfortunately, primary tumor identification poses various challenges. Techniques such as serum tumor markers and imaging tests are used to identify the TOO, although only 30% of these tests are successful. Moreover, some positive findings can be misleading [6] and CUP diagnostic workups are often time-consuming, expensive, and unsuccessful [7]. These difficulties have spurred interest in using genetic expression data, such as micro RNA, to identify the TOO.
JMIR Bioinform Biotech 2024;5:e56538
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The evidence concerning the impact of multivisceral oncological pancreatic resections on morbidity, mortality, and long-term survival across varied tumor entities is characterized by heterogeneity [5,11]. Consequently, formulating evidence-based decisions becomes a formidable challenge.
We plan to conduct a systematic review with meta-analysis to summarize the currently available evidence on morbidity, mortality, and long-term survival in these extensive interventions.
JMIR Res Protoc 2024;13:e54089
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