Neurology and Neurosciences

The White Matter Hyperintensity Shape and Brain Clearance (WHIMAS) Study for Identification of Novel 7T Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease: Protocol for a Cross-Sectional Study

Jasmin Annica Kuhn-Keller, Ingmar Eiling, Lydiane Hirschler, Lena Václavů, Marie-Noëlle Witjes-Ané, Marjolein Wijngaarden, Martijn Nagtegaal, Ece Ercan, Nathaly Rius Ottenheim, Marjan van der Elst, Evelien Sohl, Mark A van Buchem, Simon Mooijaart, Matthias JP van Osch, Jeroen de Bresser

JMIR Res Protoc 2025 (Dec 04); 14:e77681

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Acceptance and Commitment Training for Family Caregivers of People with Neurodevelopmental Disabilities: Protocol for a Collaborative Implementation Study

Kenneth Fung, Yona Lunsky, Kendra Thomson, Lee Steel, Soumya Mishra, Jodie Siu, Nicole Bobbette, Carly Magnacca, Jonathan Weiss, Melanie Penner, Ullanda Niel, Dorothee Chopamba, Sheila Phillips, Avra Selick, Brianne Redquest, Johanna Lake

JMIR Res Protoc 2025 (Dec 04); 14:e75049

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Effects of Progressive Aerobic Training on Executive-Reward Network Connectivity and Symptoms of Internet Gaming Disorder: Randomized Controlled Trial

Shaoyu Cui, Xuefeng Xu, Xin Luo, Meiting Wei, Guang-Heng Dong

JMIR Serious Games 2025 (Nov 28); 13:e83597

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Increasing Physical Activity via Provider Support and Engagement Using a Digital Health Platform in Adults With Multiple Sclerosis: Protocol for a Randomized Controlled Trial

Dawn M Ehde, Sarah B Simmons, Kevin N Alschuler, Tracy E Herring, Andrew T Humbert, Susan R Robles, Otari Ioseliani, Karla Landis, Laurie B Kavanagh, Cindy Y Lin

JMIR Res Protoc 2025 (Nov 21); 14:e72213

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Changing the Perceived Pain Intensity in Populations With Spinal Cord Injury and With Health Disparities (HAPPINESS): Protocol for a Feasibility Study

Ann Van de Winckel, Lin Zhang, Kelvin O Lim, Leslie R Morse, Brianna Woodliff, Gladys Maestre, Kelsey Baker

JMIR Res Protoc 2025 (Nov 19); 14:e82431

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Dynamic Assessment of Fine Motor Control and Vocalization in Parkinson Disease Through a Smartphone App: Cross-Sectional Study of Time-Severity Interaction Effects

Youho Myong, Seo Jung Yun, Kyudong Park, Byung-Mo Oh, Han Gil Seo

JMIR Mhealth Uhealth 2025 (Nov 13); 13:e69028

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Effects of a Transtheoretical Model–Based mHealth Intervention on Transition Readiness in Adolescents With Epilepsy: Quasi-Experimental Study

Qing Xia, Shuangzi Li, Ting Wang, Mingping Fan, Jie Xia, Lingling Xie, Huaying Yin

JMIR Mhealth Uhealth 2025 (Nov 11); 13:e70085

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Acute Adenosine Receptor Antagonism in Combination With Acute Intermittent Hypoxia to Promote Breathing Plasticity in Amyotrophic Lateral Sclerosis: Protocol for a Randomized, Double-Blinded, Placebo-Controlled Trial

Priscila Sales de Campos, May Smith-Hublou, Wendy L Olsen, Wagner Souza Leite, James P Wymer, Nicholas J Napoli, Alicia K Vose, Michael T Pulley, Gordon S Mitchell, Barbara K Smith

JMIR Res Protoc 2025 (Nov 07); 14:e76105

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Digital Innovations for Clinical Assessment in Acquired Brain Injury: Scoping Review

Carl O'Brien, Aoife Murray, Gerard McManus, Chantel Debert

J Med Internet Res 2025 (Nov 05); 27:e73331

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Mobile Health App for Adults with Persisting Postconcussion Symptoms: Development and Usability Study

Gøril Storvig, Anker Stubberud, Johanne Rauwenhoff, Liv Marie Rønhovde, Martijn Smits, Simen Berg Saksvik, Toril Skandsen, Erling Tronvik, Alexander Olsen

JMIR Hum Factors 2025 (Nov 04); 12:e75323

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Augmented Reality Framework to Measure and Analyze Eye–Hand Coordination in Stroke Patients with Unilateral Neglect: Proof-of-Concept Study

Jonathan Becker, Sophokles Ktistakis, Mirko Meboldt, Thomas Nyffeler, Dario Cazzoli, Quentin Lohmeyer

JMIR XR Spatial Comput 2025 (Nov 03); 2:e70985

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Wearable Artificial Intelligence for Epilepsy: Scoping Review

Sarah Aziz, Amal A M Ali, Hania Aslam, Noor ul Ain, Amna Tariq, Zain Sohail, Sofia Murtaza, Hafiza Iqra Mahmood, Muhammad Irfan Wazeer, Fozia Murtaza, Alaa Abd-alrazaq, Mohammed Alsahli, Rafat Damseh, Rawan AlSaad, Tariq Shahzad, Arfan Ahmed, Javaid Sheikh

J Med Internet Res 2025 (Oct 31); 27:e73593

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Changes in Gut Microbiome Following Acupuncture and Moxibustion in Patients With Parkinson Disease: Protocol for a Single-Group, Prospective, Observational Study

Han-Gyul Lee, Seungwon Kwon, Mijung Yeom, Sun-Young Bae, Hi-Joon Park

JMIR Res Protoc 2025 (Oct 29); 14:e76551

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Evaluating Web Retrieval–Assisted Large Language Models With and Without Whitelisting for Evidence-Based Neurology: Comparative Study

Lars Masanneck, Paula Zoe Epping, Sven G Meuth, Marc Pawlitzki

J Med Internet Res 2025 (Oct 29); 27:e79379

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Application of Commonly Used Physical Tests in a Virtual Environment in Patients With Concussion to Patients With Various Types and Severities of Acquired Brain Injury: Prospective Cohort Method Comparison Study

Keely Barnes, Heidi Sveistrup, Mark Bayley, Michel Rathbone, Monica Taljaard, Mary Egan, Martin Bilodeau, Motahareh Karimijashni, Shawn Marshall

J Med Internet Res 2025 (Oct 27); 27:e76995

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An Exploration of How Functional Neurological Disorder Is Discussed on X (Twitter): Mixed Methods Study Using Social Network and Content Analysis

Caoimhe McLoughlin, Jing-Yi Wang, Florence Do, Takamichi Kanbayashi, Anna Couturier, Alan Carson, Jon Stone

J Med Internet Res 2025 (Oct 17); 27:e73439

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Parental Use of Social Media and the Internet in the Context of Their Child’s Genetic Neurodevelopmental Disorder: Mixed Methods Study Nested in the GenROC Cohort Study

Karen Jaqueline Low, Georgia Treneman-Evans, Sarah L Wynn, Jenny Ingram, John Powell

JMIR Pediatr Parent 2025 (Oct 14); 8:e76526

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Comparative Study of the Quality of Life of Patients With Ototoxicity Due to Platinum-Based Chemotherapy, With Hearing Aid Versus Those Without: Study Protocol for a Randomized Pilot Study—The PROTOTOX Study

Romina Mastronicola, Elise Kayser, Yolanda Fernandez, Gilles Dolivet

JMIR Res Protoc 2025 (Oct 10); 14:e71562

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Ankle Bracelet Laser as a Novel Portable Device to Improve Walking in Patients With Parkinsonism: Randomized Crossover Controlled Trial

Peeraya Ruthiraphong, Kwan Srisilpa, Chompoonuch Ratanasutiranont

JMIR Rehabil Assist Technol 2025 (Oct 07); 12:e70209

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The Use of Repetitive Transcranial Magnetic Stimulation to Improve Cognitive Impairment in Patients With Stroke Based on rs-fMRI Findings: Protocol for a Meta-Analysis

Xin Xiang, Hao Li, Lin Lu, Yuting Cao, Chunzhen Li, Lubo Xiao, Furong Liu, Yi Ran, Hong Zhang, Ning Zhao

JMIR Res Protoc 2025 (Oct 02); 14:e77931

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