Precision Medicine and Genetics

Articles published in this theme: 86 (scroll down to load remaining articles)

2026

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Kidney-Tonifying, Phlegm-Resolving, and Blood Stasis–Removing Therapy for Multiple Myeloma: Protocol for a Randomized Controlled Trial on Epigenetic and Immune Modulation

Xiaoqi Sun, Yongming Zhou, Yujue Wang, Youya Dai, Wenwei Zhu, Hailin Chen

JMIR Res Protoc 2026 (Mar 05); 15:e86322

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Cumulative Stress Burden and Association With DNA Methylation in Ethiopian American Immigrants: Protocol for a Community-Engaged, Biopsychosocial Study

Lara Stone, Lili Ding, Meron Hirpa Kassa, Beakal Amsalu, Bruktawit Getnet, Hermella Eshete, Tesfaye Mersha, Lisa M Vaughn

JMIR Res Protoc 2026 (Feb 10); 15:e85971

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Screen Time and Chronic Pain Health: Mendelian Randomization Study

Jiahui Jiang, Chunyan Pu, Jiarui Cai, Chuan Yu, Zhenmi Liu, Chenghan Xiao

J Med Internet Res 2026 (Feb 09); 28:e78233

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Development of Venous Thromboembolism Risk Prediction Models Based on Whole Blood Gene Expression Profiling Using 20 Machine Learning Algorithms: Comprehensive Analysis Study

Yedong Huang, Xiaoyun Chen, Guannan Bai, Yajun Zhao, Dapeng Kuang, Lin Zhang, Wei Lu

JMIR Med Inform 2026 (Jan 16); 14:e75565

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Unpacking Genomic Biomarkers for Programmed Cell Death Receptor-1 Immunotherapy Success in Non–Small Cell Lung Cancer Using Deep Neural Networks: Quantitative Study

Rayan Mubarak, Fahim Islam Anik, Jean T Rodriguez, Nazmus Sakib, Mohammad A Rahman

JMIR Bioinform Biotech 2026 (Jan 13); 7:e70553

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2025

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Accelerometer-Derived Rest-Activity Rhythm Amplitude, Genetic Predisposition, and the Risk of Ischemic Heart Disease: Observational and Mendelian Randomization Study

Lele Wang, Juying Zhang, Xiong Xiao, Xuewei Tang, Jianxiang Tang, Hao Xu, Bing Guo, Xing Zhao

J Med Internet Res 2025 (Dec 15); 27:e79301

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Protein-Protein Interactions in Papillary and Nonpapillary Urothelial Carcinoma Architectures: Comparative Study

Charissa Chou, Yiğit Baykara, Sean Hacking, Ali Amin, Liang Cheng, Alper Uzun, Ece Dilber Gamsiz Uzun

JMIR Bioinform Biotech 2025 (Nov 27); 6:e76736

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Effects of Communicating Genetic Risk of Type 2 Diabetes and Wearable Technologies on Behavioral Outcomes in East Asians: Statistical Analysis Protocol for a Randomized Controlled Trial

Harrison Hin Sheung Ho, Ziyuan Chen, Job Godino, Michael Multhaup, Derwin King Chung Chan, Shiu Lun Au Yeung, Shan Luo, Brian Hon Yin Chung, Simon Griffin, Youngwon Kim

JMIR Res Protoc 2025 (Nov 05); 14:e65012

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Association of Modifiable Lifestyle and Metabolic Factors With the Risk of Developing Sepsis: 2-Sample Mendelian Randomized Study

Haifeng Lv, Jing Liu, Yelin Cao, Weina Fan, Guojie Shen, Feifei Wang, Qingqing Ye, Xiaoliang Wu, Kaijin Xu

Interact J Med Res 2025 (Nov 03); 14:e72244

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Evaluating Patient Experience With Genomic Medicine: A Content Analysis of National Cancer Institute–Designated Cancer Centers’ Websites

Amanda Sara Andriessen, Loren Saulsberry

JMIR Cancer 2025 (Oct 21); 11:e76549

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A Social Media Campaign and Web-Based Survey About Prostate Cancer Genetics: Mixed Methods Study

Amy E Leader, Stacy Loeb, Preethi Selvan, Ashley Hunter, Rebecca Hartman, Scott W Keith, Veda N Giri

JMIR Cancer 2025 (Oct 14); 11:e69787

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Investigating the Role of Coenzyme A Restriction in the Pathophysiology of Preeclampsia: Protocol for a Combined Patient Screening and Laboratory Study

Reem Al-Jayyousi, Reem K Jan, Alexander D Giddey, Adrian G Stanley, Anagha Parambath, Fadi G Mirza, Rajan Radhakrishnan, William Atiomo, Charlie Hodgman

JMIR Res Protoc 2025 (Oct 03); 14:e66202

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Clinical Utility of Early Intervention Including the 5-Step Precision Medicine Method in First-Episode Psychosis: Protocol for a Cohort Study With Nested Economic and Process Evaluations

Jesús Pérez, David Heredero Jung, Óscar Gonzalo, Belén García Berrocal, Carmen García Cerdán, Pablo Salas Aranda, Alejandro de la Sota Pérez, Sandra Milagros Lorenzo Hernández, Elena Marcos Vadillo, Rocío García García, Vanesa Berdión Marcos, Ana Maciá Casas, Belén Refoyo Matellán, Berta Bote Bonaechea, Llanyra García Ullán, Carolina Lorenzo Romo, Carmen Martín Gómez, Concha Turrión Gómez, María Isidoro García

JMIR Res Protoc 2025 (Sep 23); 14:e74408

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Bridging Technology and Pretest Genetic Services: Quantitative Study of Chatbot Interaction Patterns, User Characteristics, and Genetic Testing Decisions

Yang Yi, Lauren Kaiser-Jackson, Jemar R Bather, Melody S Goodman, Daniel Chavez-Yenter, Richard L Bradshaw, Rachelle Lorenz Chambers, Whitney F Espinel, Rachel Hess, Devin M Mann, Rachel Monahan, David W Wetter, Ophira Ginsburg, Meenakshi Sigireddi, Kensaku Kawamoto, Guilherme Del Fiol, Saundra S Buys, Kimberly A Kaphingst

J Med Internet Res 2025 (Sep 17); 27:e73391

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Evaluating the Effect of a Molecular Point-of-Care Test on Acute Respiratory Infections in General Practice: Protocol for a Cluster Randomized Trial

Kirubakaran Balasubramaniam, Line Maria Simonsen, Line Planck Kongstad, Trine Thilsing, Sonja Wehberg, Jesper Hallas, Liza Sopina, Jesper Bo Nielsen, Gritt Overbeck, Elisabeth Assing Hvidt, Dorte Ejg Jarbøl, Tina Lein Rasmussen, Jens Søndergaard

JMIR Res Protoc 2025 (Sep 08); 14:e72842

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Surveillance of the Genetic Signature in Circulating Tumor DNA for Guiding Adjuvant Chemotherapy in Urothelial Carcinoma: Protocol for a Pilot Randomized Controlled Trial

Yongle Zhan, Xiaohao Ruan, Yishuo Wu, Tsun Tsun Stacia Chun, Chi Yao, Ruofan Shi, Jiacheng Liu, Salida Ali, Ruochen Ma, Da Huang, Yi Gao, Ying Xu, Lu Chen, Qijun Du, Ada Tsui-Lin Ng, Cho Wing Bryan Li, Danfeng Xu, Rong Na

JMIR Res Protoc 2025 (Aug 26); 14:e72597

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An eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Patients With Metastatic Cancers: Protocol for a Randomized Trial

Kimberley T Lee, Briana McLeod, Brian Egleston, Sarah Brown, Sarah Howe, Dominique Fetzer, Lauren Gutstein, Cara Cacioppo, Dana Clark, Susan M Domchek, Jessica Ebrahimzadeh, Dana Falcone, Demetrios Ofidis, Hannah Griffin, Rajia Mim, Santina Hernandez, Linda Fleisher, Kelsey Karpink, Enida Selmani, Aysha Tahsin, Lynne Wagner, Michelle Weinberg, Kuang Yi-Wen, Elisabeth Wood, Angela R Bradbury

JMIR Res Protoc 2025 (Aug 25); 14:e72515

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Lipid Profile and Apolipoprotein B Serum Levels in the Vietnamese Population With Newly Diagnosed Elevated Low-Density Lipoprotein Cholesterol and Association With the Single-Nucleotide Variant rs676210: Cross-Sectional Study

Quyen Thuy Nguyen, An Viet Tran, Bao The Nguyen, Hoa Thai Nguyen, Nhung Thi Hong Thai, Hen Huu Phan

JMIR Cardio 2025 (Aug 07); 9:e76850

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Sarcopenia and Risk of Cognitive Impairment: Cohort Study and Mendelian Randomization Analysis

Tingting Sha, Yuqing Zhang, Jie Wei, Changjun Li, Chao Zeng, Guanghua Lei, Yilun Wang

JMIR Aging 2025 (Jun 11); 8:e66031

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Next-Generation Sequencing–Based Testing Among Patients With Advanced or Metastatic Nonsquamous Non–Small Cell Lung Cancer in the United States: Predictive Modeling Using Machine Learning Methods

Alan James Michael Brnabic, Ilya Lipkovich, Zbigniew Kadziola, Dan He, Peter M Krein, Lisa M Hess

JMIR Cancer 2025 (Jun 11); 11:e64399

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